The Aprilia RS 457 is powered by a 457cc parallel-twin, liquid-cooled engine producing 47.6hp and 43.5Nm of torque, paired with a 6-speed gearbox. 

The RS 457 was initially offered in three colour schemes – Opalescent Light, Prismatic Dark, and Racing Stripes. Three new colours – Coral Blue Snake, Arsenic Yellow, and a MotoGP Replica edition – were unveiled at IBW 2025. The GP Replica colourway comes with a quickshifter and adjustable brake lever as standard. The rest of the bike remains mechanically identical to the standard RS 457.